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Chinese scientists develop electrode coating to address signal loss and tissue adhesion problems in long-term brain-computer interface implantation_我的网站

一 |     It’s Halloween, the one night when it’s totally okay to grab popcorn, turn off the lights, and scare yourself. Whether you love ghosts, creepy clowns, or haunted houses, there’s something thrilling about watching a good horror movie. From chilling Hollywood classics to Indian gems that redefine fear, here are ten perfect horror movies to make your Halloween 2025 extra spooky.     In This Article      The Shining (1980)The Ring (2002)Jennifer’s Body (2009)The Conjuring (2013)IT (2017)Hereditary (2018)Tumbbad (2018)The Curse of La Llorona (2019)Smile (2022)The Monkey (2024)The Shining (1980)                                                  Directed by Stanley Kubrick and starring Jack Nicholson, The Shining follows a writer who slowly loses his mind while caretaking a remote hotel with his family. With its eerie atmosphere, famous “Here’s Johnny!” scene, and haunting visuals, this classic still defines horror.     The Ring (2002)                                                  Watch a cursed videotape and you’ll die in seven days, that’s the terrifying premise of The Ring. Naomi Watts stars as a journalist trying to uncover the truth before her time runs out. Even decades later, that creepy girl crawling out of the TV remains unforgettable.     Jennifer’s Body (2009)                                                  When a high school girl (played by Megan Fox) becomes possessed by a demon, she starts feeding on her male classmates. Darkly funny and full of sharp one-liners, Jennifer’s Body has become a cult favourite for its mix of horror, feminism, and high school chaos.     The Conjuring (2013)                                                  Based on real-life paranormal investigators Ed and Lorraine Warren, The Conjuring follows a family who moves into a farmhouse only to find something terrifying lurking inside. Patrick Wilson and Vera Farmiga deliver unforgettable performances in this ghostly tale that started a whole horror universe.     IT (2017)                                                  A group of kids in a small town face their biggest fear, a clown named Pennywise who feeds on children. Based on Stephen King’s novel, IT is both terrifying and heartfelt, with Bill Skarsgård’s performance as Pennywise sending chills down spines everywhere.     Hereditary (2018)                                                  When a mysterious grandmother dies, her family begins to unravel dark secrets that connect them to something truly evil. Starring Toni Collette in a stunning performance, Hereditary mixes family drama with shocking horror that slowly crawls under your skin.     Tumbbad (2018)                                                  An Indian horror masterpiece, Tumbbad tells the story of a man obsessed with finding hidden treasure in a cursed village. Set against the backdrop of colonial India, this movie is visually stunning and deeply haunting that blends greed, mythology, and fear perfectly.     The Curse of La Llorona (2019)                                                  Inspired by the Latin American legend of the Weeping Woman, this film follows a mother who tries to protect her children from a ghostly woman searching for lost kids. It’s spooky, emotional, and full of classic jump scares, perfect for a Halloween night watch.     Smile (2022)                                                  After witnessing a patient’s strange death, a therapist starts experiencing terrifying visions and eerie smiles everywhere she goes. Smile isn’t just jump scares, it’s a chilling take on trauma and how fear spreads like a curse.     The Monkey (2024)                                                  Based on a Stephen King short story, The Monkey follows twin brothers who discover their father’s old toy monkey, one that seems to cause a death every time it claps its tiny cymbals. It’s creepy, emotional, and a must-watch for anyone who loves supernatural horror.     So, dim the lights, grab your snacks, and pick a movie or two from this list to set the Halloween mood. Whether it’s ghosts, curses, or creepy toys, these stories remind us why we love horror movies.Also Read: Top 10 Horror Movies of All Time: The Exorcist & More。    

    Photo: VCG
Chinese researchers have developed a multifunctional electrode coating that addresses key challenges in long-term brain-computer interface (BCI) implantation, including signal loss and tissue adhesion, bringing BCI one step closer to clinical application, the Global Times learned from the research team behind the findings on Sunday. 
As an emerging field combining neuroscience and artificial intelligence (AI), BCI faces a major challenge of ensuring long-term compatibility between electrodes and brain tissue. Previous clinical trials showed that immune responses could cause implanted electrodes to retract after just three months, severely reducing signal quality and the number of available channels. 
This problem stems from chronic inflammation triggered by implants, which creates insulating scar tissue around electrodes and separates them from neurons. Irreversible adhesion between electrodes and brain tissue after long-term implantation also makes device removal risky, potentially causing brain injury during follow-up surgeries.
Experiments showed that flexible neural electrodes coated with this material could operate stably in the brain for more than 300 days and could be safely removed without causing damage. This means the universal coating technology can make electrodes not only operate stably over the long term but can also be safely removed and replaced after aging, paving the way for long-term BCI applications.
Developed by the research team led by Zhang Wei at the Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, associated with Beijing Tiantan Hospital, Shanghai Institute of Microsystem and Information Technology and NeuroXess, a high-tech life science company specializing in BCI technologies, the cationic alternating peptide electrode coating preserves electrode flexibility and conductivity, while offering antibacterial, anti-protein adsorption and immune-rejection-inhibiting functions. 
A 300-day animal study showed the coating's effectiveness. Bare electrodes experienced a sharp loss of recording capability after 90 days of implantation and could barely detect neuronal signals after 300 days. In contrast, coated electrodes maintained stable recording channels and consistently captured neural signals above 155 microvolts. 
In terms of neural modulation, after 300 days of implantation, conventional electrodes required a current of 100 microamps to induce weak limb responses, while coated electrodes triggered clear movements with only 2 microamps, improving modulation efficiency by 50 times. 
Notably, the removal tests highlighted a key advantage of the coating that electrodes no longer form irreversible bonds with brain tissue. In the experiments, the coated electrodes were removed intact, with minimal damage to the surrounding brain tissue, Zhang told the Global Times on Sunday.
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